Publicación

Tipo de publicación: Artículos científicos (Publicados en revistas de divulgación o científicas)

Título del artículo: In vitro antiviral activity and phytochemical screen in the extracts of peels from four species of tropical fruits collected in Merida Yucatan, Mexico

Registrado por: José Alberto Mendoza-Espinoza

Año de publicación:

Resumen: The objective of this study was to investigate extracts from the peels of Annona squamosa L. (purple sugar apple), Annona reticulata L. (custard apple), Chrysophyllum cainito L. (green star apple), and Melicoccus bijugatus Jacq. (mamoncillo), as potential sources of anti-HIV-1 agents. Methanolic extracts from the peels of the aforementioned tropical fruits were obtained by maceration.
Antiviral activity was evaluated through HIV-1 RT inhibition by
extracts, using a non-radioactive immuno/colorimetric assay (Lenti
RT Activity Assay, Cavidi Tech). Assay was performed according to
the protocol provided by the manufacturer. Extracts from the peels
of A. squamosa, A. reticulata, and C. cainito showed high antiviral activity, with HIV-1 reverse transcriptase inhibition values of 96.45 ±
2.08%, 78.63 ± 0.97%, and 72.55 ± 2.26%, respectively. These results
demonstrate that A. squamosa, A. reticulata, and C. cainito have significant antiviral activity in their peels and can therefore be regarded as potential sources of anti-HIV-1 agents.

Editorial:

Número de páginas:

Autor(es): Chel-Guerrero LD, R Gómez-Cansino, SL Gúzman-Gutierrez, MG Campos-Lara, E Saury-Duch, F Díaz de León Sánchez, R Reyes-Chilpa, JA Mendoza-Espinoza

Campo: Biología y Química

Disciplina: Salud

Subdisciplina:

Número de registro: Doi: 10.32604/phyton.2018.87.068