Publicación

Tipo de publicación: Artículos científicos (Publicados en revistas de divulgación o científicas)

Título del artículo: In Vivo Anti-Inflammatory Effect, Antioxidant Activity, and Polyphenolic Content of Extracts from Capsicum chinense By-Products

Registrado por: Ingrid Mayanín Rodríguez Buenfil

Año de publicación: 2022

Resumen: By-products of Capsicum chinense Jacq., var Jaguar could be a source of bioactive compounds.
Therefore, we evaluated the anti-inflammatory effect, antioxidant activity, and their relationship with the polyphenol content of extracts of habanero pepper by-products obtained from plants grown
on black or red soils of Yucatán, Mexico. Moreover, the impact of the type of extraction on their activities was evaluated. The dry by-product extracts were obtained by maceration (ME), Soxhlet
(SOX), and supercritical fluid extraction (SFE). Afterward, the in vivo anti-inflammatory effect (TPA induced ear inflammation) and the in vitro antioxidant activity (ABTS) were evaluated. Finally, the
polyphenolic content was quantified by Ultra-Performance Liquid Chromatography (UPLC), and its correlation with both bioactivities was analyzed. The results showed that the SFE extract of stems of plants grown on red soil yielded the highest anti-inflammatory effect (66.1  3.1%), while the extracts obtained by ME and SOX had the highest antioxidant activity (2.80 +/- 0.0052 mM Trolox equivalent) and polyphenol content (3280+/- 15.59 mg*100 g-1 dry basis), respectively. A negative correlation between the anti-inflammatory effect, the antioxidant activity, and the polyphenolic content was found. Overall, the present study proposed C. chinense by-products as a valuable source of compounds with anti-inflammatory effect and antioxidant activity.

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Autor(es): Lilian Dolores Chel-Guerrero, Gabriela Castañeda-Corral, Misael López-Castillo, Matteo Scampicchio, Ksenia Morozova, Julio Enrique Oney-Montalvo, Giovanna Ferrentino, Juan José Acevedo-Fernández, and Ingrid Mayanín Rodríguez-Buenfil

Campo: Biología y Química

Disciplina: Salud

Subdisciplina:

Número de registro: Doi: 10.3390/molecules27041323