Tipo de publicación: Artículos científicos (Publicados en revistas de divulgación o científicas)
Título del artículo: A Cecropia peltata ethanolic extract reduces insulin resistance and hepatic steatosis in rats fed a high-fat diet
Registrado por: International Society of Ethnopharmacology
Año de publicación: 2020
Resumen: Ethnopharmacological relevance
Cecropia peltata L. (CP) leaves have been used in Latin American traditional medicine by its purported hypoglycemic, anti-inflammatory and antioxidant properties.
Purpose
The aim of this study was to evaluate the metabolic effects of an ethanolic extract of CP leaves in rats fed a high-fat diet and 10% of sugar in water (HFD).
Methods
Male Wistar rats were randomly divided into four groups: group 1 was fed a control diet; groups 2, 3 and 4 were fed a HFD. In addition, group 3 was co-administered with 10 mg/kg/day of CP extract (HFD + CP) and group 4 with a solution of 5 mg/kg/day metformin (HFD + M) for 90 days.
Results
Body weight gain and serum triglycerides were significantly decreased in the HFD + CP group compared with the HFD and HFD + M groups. Glucose tolerance increased in the HFD + CP compared with the HFD group. Administration with CP extract reduced …
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Autor(es): Andrea Duarte-Alonso, Trinidad Eugenia Cu-Cañetas, Azalia Avila-Nava, Delia Sansores-España, Juan José Acevedo-Fernández, Mukthar Sandoval-Peraza, Luis Chel-Guerrero, Ivan Torre-Villalvazo
Campo: Ciencias biológicas
Disciplina: Biología
Subdisciplina:
Número de registro: Print ISSN: 0378-8741Online ISSN: 1872-7573